Customs - CBIC has issued Circular No. 10/2022 dated 25 July 2022 to clarify on the Electro chemiluminescence Immuno Assay (ECLIA) kits wherein it has been clarified that Chemiluminescence Immuno assay (CLIA) is a self-sufficient kit which provides a sensitive, high throughput alternative to conventional colorimetric methodologies. In Chemiluminescence Immuno assay (CLIA), the luminescence is produced as a result of chemical reaction where as in Electro Chemiluminescence lmmuno assay (ECLIA). The luminescence is produced as a result of electrochemical reaction. The CLIA and ECLIA can accommodate many immunoassay principles while providing superior performance and the applications, uses of both the techniques are same. Hence, both CLIA and ECLIA are one and the same.
